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A new method of making diamonds doesn’t require extreme pressure 

Lab-grown diamonds can form at atmospheric pressure in a liquid of gallium, iron, nickel and silicon.

How a sugar acid crucial for life could have formed in interstellar clouds

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More Stories in Chemistry

These are the chemicals that give teens pungent body odor

Steroids and high levels of carboxylic acids in teenagers’ body odor give off a mix of pleasant and acrid scents.

The smallest known molecular knot is made of just 54 atoms

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Here’s how tardigrades go into suspended animation

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Capturing methane from the air would slow global warming. Can it be done?

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‘Most Delicious Poison’ explores how toxins rule our world

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Light, not just heat, might spur water to evaporate

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Salty sweat helps one desert plant stay hydrated

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The development of quantum dots wins the 2023 Nobel prize in chemistry

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50 years ago, the quest for superheavy elements was just getting started

In the 1970s, scientists were on the hunt for superheavy elements. They’ve since found more than a dozen and are searching for more.

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Researchers detect a new molecule in space

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New research from the group of MIT Professor Brett McGuire has revealed the presence of a previously unknown molecule in space. The team's open-access paper, “ Rotational Spectrum and First Interstellar Detection of 2-Methoxyethanol Using ALMA Observations of NGC 6334I ,” appears in April 12 issue of The Astrophysical Journal Letters .

Zachary T.P. Fried , a graduate student in the McGuire group and the lead author of the publication, worked to assemble a puzzle comprised of pieces collected from across the globe, extending beyond MIT to France, Florida, Virginia, and Copenhagen, to achieve this exciting discovery. 

“Our group tries to understand what molecules are present in regions of space where stars and solar systems will eventually take shape,” explains Fried. “This allows us to piece together how chemistry evolves alongside the process of star and planet formation. We do this by looking at the rotational spectra of molecules, the unique patterns of light they give off as they tumble end-over-end in space. These patterns are fingerprints (barcodes) for molecules. To detect new molecules in space, we first must have an idea of what molecule we want to look for, then we can record its spectrum in the lab here on Earth, and then finally we look for that spectrum in space using telescopes.”

Searching for molecules in space

The McGuire Group has recently begun to utilize machine learning to suggest good target molecules to search for. In 2023, one of these machine learning models suggested the researchers target a molecule known as 2-methoxyethanol. 

“There are a number of 'methoxy' molecules in space, like dimethyl ether, methoxymethanol, ethyl methyl ether, and methyl formate, but 2-methoxyethanol would be the largest and most complex ever seen,” says Fried. To detect this molecule using radiotelescope observations, the group first needed to measure and analyze its rotational spectrum on Earth. The researchers combined experiments from the University of Lille (Lille, France), the New College of Florida (Sarasota, Florida), and the McGuire lab at MIT to measure this spectrum over a broadband region of frequencies ranging from the microwave to sub-millimeter wave regimes (approximately 8 to 500 gigahertz). 

The data gleaned from these measurements permitted a search for the molecule using Atacama Large Millimeter/submillimeter Array (ALMA) observations toward two separate star-forming regions: NGC 6334I and IRAS 16293-2422B. Members of the McGuire group analyzed these telescope observations alongside researchers at the National Radio Astronomy Observatory (Charlottesville, Virginia) and the University of Copenhagen, Denmark. 

“Ultimately, we observed 25 rotational lines of 2-methoxyethanol that lined up with the molecular signal observed toward NGC 6334I (the barcode matched!), thus resulting in a secure detection of 2-methoxyethanol in this source,” says Fried. “This allowed us to then derive physical parameters of the molecule toward NGC 6334I, such as its abundance and excitation temperature. It also enabled an investigation of the possible chemical formation pathways from known interstellar precursors.”

Looking forward

Molecular discoveries like this one help the researchers to better understand the development of molecular complexity in space during the star formation process. 2-methoxyethanol, which contains 13 atoms, is quite large for interstellar standards — as of 2021, only six species larger than 13 atoms were detected outside the solar system , many by McGuire’s group, and all of them existing as ringed structures.  

“Continued observations of large molecules and subsequent derivations of their abundances allows us to advance our knowledge of how efficiently large molecules can form and by which specific reactions they may be produced,” says Fried. “Additionally, since we detected this molecule in NGC 6334I but not in IRAS 16293-2422B, we were presented with a unique opportunity to look into how the differing physical conditions of these two sources may be affecting the chemistry that can occur.”

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• ACS Publications

28 Must-Read Topics in Chemistry

• Mar 4, 2021
• 14 min read

ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research […]

ACS Publications regularly produces collections of the most important chemistry research topics. These Virtual Collections of the most important chemistry research topics bring together the most important ideas in the field in a variety of ways, including Special Issues and ACS Selects from across the portfolio journals. These collections reflect the most important chemistry research topics of current scientific interest and are designed for experienced investigators and educators alike.

Browse 28 of the most important, engaging topics in chemists with Virtual Collections released by ACS Publications journals in Q4 2020:

Crystalline molecular materials: from structure to function.

This Virtual Special Issue focuses on the design and study of materials wherein the target properties arise from, or are enhanced by, the three-dimensional assembly of molecules in a solid phase. The “structure−function” relationship transcends the nature of the individual molecule, and supramolecular organization is a key component in the material’s properties. The goal of this issue is to assemble contributions from a broad community of scientists with similar research interests, as defined by the need to understand and manipulate the bulk assembly of molecules. Placing emphasis on a common interest in supramolecular architecture, this issue showcases work in apparently disparate fields, including molecule-based magnetism, rare zero thermal expansion properties, and catalytic activity.

Read the Issue. ***

Materials for Thermoelectric Energy Conversion

This virtual issue of ACS Applied Materials & Interfaces and ACS Applied Energy Materials presents cutting edge articles in the field of Thermoelectric Energy Conversion. Thermoelectric materials and devices are central for energy conversion and management as they convert waste heat into electricity. Given the ubiquitous nature of heat, thermoelectric materials provide total-package solutions to mitigate environmental crisis and energy needs. The realization of this has caused a surge in the development of high-performance, environmentally benign, robust, and earth-abundant inorganic materials, which can be used in heat to electrical energy generations in power plants, space, automobiles, households, battery technology, and data centers. Interestingly, flexible thermoelectric materials, mainly based on organic/polymer materials, have successfully been integrated into body-worn fabrics and watches, which simply utilize body heat to generate electricity. Furthermore, using the Peltier effect, thermoelectric coolers are developed and are one of the mainstays in the consumer market for refrigeration purposes, especially for portable applications. Hence, thermoelectricity is foreseen as a potential frontrunner in energy management for the near future.

Interfacialscience Developments at the Chinese Academy of Sciences

This virtual issue is a sampling of some of the most recent work from the Chinese Academy of Sciences, with an emphasis on work from this year (2020) so far. The 46 articles in this virtual issue cover a broad range of research topics, examples of which include Janus particle engineering and interfacial assembly, surface modification of colloid particles, stability of water monolayer in mineral under high pressure, nano-bubbles adsorption on surface, switching of underwater superhydrophilicity and superoleophobicity, nanostructured de-icing surface, lithium ion battery anode binder, bio-inspired smart liquid directional transport control, corrosion resistance of alloys, behavior of polymers at solid/liquid interface, and effect of polymer conformation on protein resistance.

Celebrating 90% Completion of the Human Proteome

Twenty years after the establishment of the international Human Proteome Organization (HUPO) and ten years after its launch of the Human Proteome Project (HPP), researchers have much to celebrate. Today, HUPO will release the draft human proteome at the 19th Human Proteome Organization World Congress, connecting virtually, with this Virtual Issue published in the Journal of Proteome Research.

Read the Issue . ***

Nanomaterials-based Membranes for Chemical Separations

Membranes are a critical area of research in academia and have been used in industrial applications for decades. Membrane-based separations are desired in industry because they can be highly energy efficient and up to an order of magnitude less expensive than other techniques such as distillation. In addition, these separations are easily scaled to industrial levels so that advances in the laboratory can be translated to real applications. The key challenges in this field are how to separate chemicals with similar sizes by having a high flux for only one chemical through a membrane. This difference in flux should translate into a high selectivity for one chemical over one or more other chemicals present in a mixture. An unfortunate trade-off in membrane-based separations is that as the permeation of a chemical increases, the selectivity of the membrane will often decrease. To address these challenges, scientists often use cross-linked polymers with ill-defined pores, hard materials such as zeolites with well-defined pores, 2D materials, coated nanofibers, carbon nanotubes, metal nanoparticles, or other nanomaterials.

Organic Chemistry in China: Synthetic Methodology, Natural Products, and More

During the past 20 years, China has become a powerhouse in chemistry research, now leading globally in submissions of research articles to chemical journals. In recognizing these developments, Organic Letters presents a Virtual Issue that includes a collection of 25 research articles contributed by Chinese chemists during 2019-2020, selected from among the more than 1,000 articles published in the journal from China over this period.

Advances in Microfluidics Research

This Virtual Issue highlights articles published in Analytical Chemistry that showcase advances in microfluidics research over the past several years. The articles below are separated by sub-field and span research on virus detection to cell manipulation to 3D-printing, and are all at the cutting edge of microfluidics technologies. The thirty articles included in this collection were selected by Associate Editor Yoshinobu Baba and include previous winners of the Chemical & Biological Microsystems Society (CBMS)/ Analytical Chemistry co-sponsored Young Innovator Award.

Chemistry in Korea: IBS and Beyond

This virtual issue of “Chemistry in Korea: IBS and Beyond” highlights the latest contributions from eight IBS centers along with exciting advances from other emerging scientists in South Korea. Topics encompass a wide range of chemistry and its cross-boundary researches from theory and simulations, nanomaterials, molecular synthesis, catalysts, spectroscopy, supramolecular chemistry, soft materials to nanomedicine.

Highlighting Analytical Chemistry 2020 Advisory Board Members

The members of Analytical Chemistry ‘s Editorial Advisory Board (EAB) and Early Career Board (ECB) panels devote substantial voluntary time and energy to support Analytical Chemistry and deserve special recognition for their contributions. In recognition of their service, this new virtual issue is dedicated to the members of both the journal’s EAB and ECB, with each selecting one of their recent Analytical Chemistry articles to highlight.

A Bright New World of Ferroelectrics: Magic of Spontaneous Polarization

Ferroelectric materials featured with spontaneous polarization have experienced a century of vigorous development. The permanent electric dipole moment makes ferroelectric an outstanding multifunctional material for a wide range of applications. Ferroelectrics with unique coupling effects among electric, optical, mechanical, thermal, and magnetic orders, have been developed for a wide range of functional devices and triggered a new world-wide wave of ferroelectric research. This virtual issue highlights some of the key state-of-the-art findings in ferroelectrics published in ACS Applied Materials & Interfaces and ACS Applied Electronic Materials , and the editorial attempts to reflect the rapid development and provide a perspective in this field.

Peter J. Rossky Festschrift

This Virtual Special Issue honors Professor Peter J. Rossky and his contributions to the field of physical chemistry.

Computational and Experimental Advances in Biomembranes

As an integral component of cellular architecture and signalling, cell membranes are central to cell physiology. Comprising a vastly heterogeneous mixture of proteins and lipids, cell membranes are constantly adapting their structural organization to regulate cellular processes. Malfunction at the level of lipid-protein interaction is implicated in numerous diseases, and hence, understanding cell membrane organization at the molecular level is of critical importance. The collection of articles in this Virtual Special Issue from The Journal of Physical Chemistry B provides a survey of the advances in both computational and experimental characterization of the complex processes underlying the behavior of cellular membranes.

Sensors and Industry

In this virtual issue, ACS Sensors and Analytical Chemistry highlight 30 of these outstanding industrial co-authored papers recently published in the two journals. The breadth of the articles in this collection emphasizes the incredible research on diagnostic methods being performed in both universities and industries, and highlights the benefits of collaboration between the two. Read the Issue . ***

Machine Learning in Physical Chemistry

Physical chemistry stands today at an exciting transition state where the integration of machine learning and data science tools into all corners of the field is poised to do nothing short of revolutionizing the discipline. These powerful techniques – when appropriately combined with domain knowledge, tools, and expertise – have led to new physical insights, better understanding, accelerated discovery, rational design, and inverse engineering that transcend traditional approaches to materials, molecular, and chemical science and engineering. This collection of nearly 150 manuscripts from The Journal of Physical Chemistry A / B / C and The Journal of Physical Chemistry Letters reflects the relevance and popularity of this topic in physical chemistry by both the depth and breadth of excellent articles in this exciting collection.

Self-Healing Materials

This is a spotlight on applications discusses developments made over the last six years that have enabled the fabrication of increasingly high-performance spray-coated perovskite solar cells. In particular, the various approaches adopted to spray-cast perovskite films (one-step vs two-step processes) ware charted and the development of sophisticated techniques used to control thin-film crystallinity is described. Finally, remaining research challenges are discussed that, once solved, may allow the mass deployment of low-cost solar energy.

Women in Mass Spectrometry

This virtual issue was assembled to feature talented women mass spectrometrists who publish in JASMS as the corresponding author. The articles compiled are among the most highly cited that were published in the journal in the last 5 years, regardless of gender, and are representative of the best mass spectrometry science reported in JASMS .

In Memory of Mario Molina (1943-2020)

Mario Molina was a Mexican chemist who shared the 1995 Nobel Prize in chemistry with the late F. Sherwood Rowland of UC Irvine and Paul Crutzen of the Max Planck Institute for Chemistry in Mainz “for their work in atmospheric chemistry particularly concerning the formation and decomposition of ozone.” Molina passed away in his birth city of Mexico City at age 77 on 7 October 2020. A physical chemist at heart, Molina published about 80 papers in The Journal of Physical Chemistry . His mentees remember him by celebrating 30 of them. His indelible legacy lives on through his publications, his collaborators, the scholars that he trained, the innovations in experimental design he made, the thousands who were inspired and informed by his science communication, and the millions whose quality of life improved thanks to his work on stratospheric ozone depletion and air quality in megacities.

Women Scientists at the Forefront of Energy Research: A Virtual Issue, Part 3

This is the third part of a series that recognizes women energy researchers who have published new advances from their laboratories in ACS Energy Letters . The inspirational stories and advice to newcomers in the field contained in this issue should provide motivation to advance the scientific research in energy conversion and storage. Through their personal reflections, these researchers discuss the successful career paths they have taken to become leaders in the scientific community.

Scalable Organic Chemistry: A Virtual Issue to highlight Organic Process Research & Development

From small-scale use in academic research to large-scale application in industrial processes, only select chemistries make the cut to be relevant throughout the scale-up process. This virtual issue showcases a collection of innovative and industrially-relevant papers on key topics from academic and industrial chemists in Organic Process Research & Development .

Virtual Issue in Memoriam of Dr. Alan Poland (1940-2020)

Dr. Alan Poland was a major influence on the development of modern molecular toxicology and the understanding of how chemicals cause cancer. He is most widely known for his groundbreaking work to explain the adverse effects of dioxins, chemicals and related environmental pollutants.

Deep Eutectic Solvents

This virtual issue focuses on scientific and engineering advances related to Deep Eutectic Solvents. It includes papers that have appeared in the last two years in ACS Sustainable Chemistry & Engineering , Industrial & Engineering Chemistry Research , Journal of Chemical & Engineering Data , and Journal of Physical Chemistry B and C .

Celebrating ACS Sensors ‘ Editorial Advisory Board

Metal-Organic Frameworks: Fundamental Study and Applications

Exciting developments in metal-organic frameworks (MOFs) are the focus of this Virtual Issue that is jointly produced by Langmuir and ACS Applied Materials & Interfaces ( ACS AMI ). These two journals publish complementary and ground-breaking work on interfacial science. ACS AMI has a strong focus on practical applications whereas Langmuir encourages reports of both fundamental and applied nature, when rational design is a highlighted feature of the work.

Inorganic Synthesis in Uncommon Reaction Media

Water and organic solvents have long been the most common reaction media for chemical synthesis. Nevertheless, given limits in solubility and the need for extreme temperatures sometimes, especially for inorganic substances, chemists have had a growing interest in moving to “uncommon” reaction media to improve the access to certain compounds or to permit the fundamental study of the behavior of chemicals under unique conditions. In this Virtual Issue, “Inorganic Synthesis in Uncommon Reaction Media,” Guest Editor Julia Chan and Associate Editor Stefanie Dehnen highlight recent reports from Inorganic Chemistry and additionally from Chemistry of Materials and Crystal Growth & Design that feature reactions taking place in currently used uncommon systems: molten metals (metal flux), molten salts (nonmetal flux), ionic liquids (ionothermal if carried out under elevated temperatures), supercritical solvents (solvothermal), and liquefied gases.

The Challenge of Antibacterial Drug Permeation and Current Advances

Recent advances in the area of drug permeation feed the pipeline of antibacterial agents with new and improved activities and keep the ever-changing landscape of antibiotic resistance effectively managed by small molecule therapeutics. The articles included in this Virtual Issue broadly represent three areas of research: 1) new experimental approaches to analyze intracellular accumulation of compounds in whole cells and compound permeation across model membranes; 2) new computational models of drug permeation across the outer membrane and integrated kinetic models of drug permeation across membranes with active efflux; and 3) new antibiotic screening campaigns and exploration of synergistic drug combinations bypassing bacterial permeation barriers.

Organic Chemistry in Japan: A Strong Foundation and Honorable Tradition

Organic chemistry has a strong foundation and honorable tradition in Japan, centering in recent decades predominantly on the development of synthetic methodologies, particularly in an interdisciplinary fashion focusing on cross-coupling and C-H activation and functionalization, the total synthesis of natural products, chemical biology research, supramolecular chemistry, and applications of (opto)electronic materials—all with an eye toward fostering international collaborations. This new Organic Letters Virtual Issue features 25 selected articles form 2019-2020 to highlight these achievements.

This virtual issue in Environmental Science & Technology ( ES&T ) marks the 50-year anniversary of the United States Environmental Protection Agency (US EPA). Recognizing this significant milestone brings an opportunity to reflect on the enormous achievements and impact this federal agency has had on the remediation and protection of the environment, reaching both domestically within the USA and globally since its official beginnings on December 2nd, 1970.

Bioconjugate Chemistry 30th Anniversary Reviews

The breadth and impact of these 30th anniversary reviews demonstrate how the Bioconjugate Chemistry of today continues the forward-looking embrace of new science and systems while maintaining the old-fashioned virtues of scientific rigor and reproducibility.

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Light-driven enzyme engineered and repurposed to catalyse unnatural reaction

By James Urquhart 2024-04-23T08:30:00+01:00

• No comments

A natural photoenzyme found in algae has been artificially evolved to perform an unnatural and entirely new function for the first time. The work, which converted fatty acid decarboxylase (FAP) into new-to-nature radical photocyclases that catalyse the formation of carbon rings, demonstrates how photoenzymes can be evolved and repurposed for biocatalytic applications.

FAP enzymes, which are activated by blue light, were first discovered in 2017 in green microalga and shown to produce hydrocarbons by catalysing the removal of carboxyl groups from long-chain fatty acid substrates. As one of only three known classes of natural photoenzymes, researchers have been keen to exploit FAP’s potential and produce environmentally-friendly natural products, including carbon-neutral hydrocarbons for fuels, chemicals and cosmetics.

‘In general, there is a dearth of biocatalytic carbon–carbon bond forming reactions,’ says Yang Yang at the University of California, Santa Barbara, US. ‘To expand the utility of biocatalysts, it is thus imperative to discover more enzymes that can make carbon–carbon bonds, which comprise the molecular framework of all organic compounds.’

Intrigued by FAPs’ potential, Yang and his colleagues were curious to see if they could engineer them to expand their catalytic repertoire and perform entirely different unnatural reactions for carbon–carbon bond formation. Now, Yang’s team, along with researchers at the University of Pittsburgh, US, have done just that by evolving a FAP into radical photocyclase variants using directed evolution – a high-throughput technique that mimics natural selection by subjecting a gene to successive rounds of mutagenesis until the desired function is reached.

However, it was not without challenges. ‘Directed evolution of FAPs was not easy at the beginning of our project [due to their limited stability for high-throughput techniques],’ explains Yang. ‘A talented postdoc of my group, Shuyun Ju, spent several months establishing a feasible experimental workflow. He identified a few key factors that played an important role in higher-throughput screening with photobiocatalytic functions.’

Source: © Shuyun Ju et al/Springer Nature Limited 2024

The proposed catalytic cycle of the photocyclase enzyme created using directed evolution. The work could have potential in greener synthesis of small molecules

Subsequently, through rounds of directed evolution, the researchers were able to suppress the native enzyme’s decarboxylase activity while simultaneously promoting cyclisation of an emerging, and photoenzymatically formed, carbon-centred radical onto an electron-deficient alkene. The result was the production of carbon-containing rings, comprising either five or six carbons.

‘We found we can access all the four stereoisomers in radical cyclisation, with three of these stereoisomers being prepared with excellent selectivities,’ says Yang. ‘The excellent tunability of fatty acid photodecarboxylases we uncovered surprised us and demonstrated the potential of these natural photoenzymes.’

‘Remarkably, the reactions proceed in high yield and enantioselectivity with broad substrate scope,’ comments biocatalysis expert Nicholas Turner at the University of Manchester, UK. ‘This interesting study further extends the emerging class of new-to-nature biocatalysts that operate via the generation of free-radical intermediates.’

‘Obviously FAP does indeed have an enormous potential for light-assisted environmentally friendly stereoselective synthesis of small molecules and that photoenzymatic synthesis in general is the way to go,’ says Pavel Müller who co-discovered FAP at the University of Paris-Saclay, France. ‘Of the three known classes of natural photoenzymes, FAP is clearly the best and potentially most versatile chassis on which to build new constructs and try new reactions.’

S Ju et al , Nat. Chem. , 2024, DOI: 10.1038/s41557-024-01494-0

• Biocatalysis
• Cyclisation
• Photocatalysts
• Photochemistry

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Home » 300+ Chemistry Research Topics

300+ Chemistry Research Topics

Table of Contents

Chemistry is a fascinating and complex field that explores the composition, properties, and behavior of matter at the molecular and atomic level. As a result, there are numerous chemistry research topics that can be explored, ranging from the development of new materials and drugs to the study of natural compounds and the environment. In this rapidly evolving field, researchers are constantly uncovering new insights and pushing the boundaries of our understanding of chemistry. Whether you are a student, a professional researcher, or simply curious about the world around you, there is always something new to discover in the field of chemistry. In this post, we will explore some of the exciting and important research topics in chemistry today.

Chemistry Research Topics

Chemistry Research Topics are as follows:

Organic Chemistry Research Topics

Organic Chemistry Research Topics are as follows:

• Development of novel synthetic routes for the production of biologically active natural products
• Investigation of reaction mechanisms and kinetics for organic transformations
• Design and synthesis of new catalysts for asymmetric organic reactions
• Synthesis and characterization of chiral compounds for pharmaceutical applications
• Development of sustainable methods for the synthesis of organic molecules using renewable resources
• Discovery of new reaction pathways for the conversion of biomass into high-value chemicals
• Study of molecular recognition and host-guest interactions for drug design
• Design and synthesis of new materials for energy storage and conversion
• Development of efficient and selective methods for C-H functionalization reactions
• Exploration of the reactivity of reactive intermediates such as radicals and carbenes
• Study of supramolecular chemistry and self-assembly of organic molecules
• Development of new methods for the synthesis of heterocyclic compounds
• Investigation of the biological activities and mechanisms of action of natural products
• Synthesis of polymeric materials with controlled architecture and functionality
• Development of new synthetic methodologies for the preparation of bioconjugates
• Investigation of the mechanisms of enzyme catalysis and the design of enzyme inhibitors
• Synthesis and characterization of novel fluorescent probes for biological imaging
• Development of new synthetic strategies for the preparation of carbohydrates and glycoconjugates
• Study of the properties and reactivity of carbon nanomaterials
• Design and synthesis of novel drugs for the treatment of diseases such as cancer, diabetes, and Alzheimer’s disease.

Inorganic Chemistry Research Topics

Inorganic Chemistry Research Topics are as follows:

• Synthesis and characterization of new metal-organic frameworks (MOFs) for gas storage and separation applications
• Development of new catalysts for sustainable chemical synthesis reactions
• Investigation of the electronic and magnetic properties of transition metal complexes for spintronics applications
• Synthesis and characterization of novel nanomaterials for energy storage applications
• Development of new ligands for metal coordination complexes with potential medical applications
• Investigation of the mechanism of metal-catalyzed reactions using advanced spectroscopic techniques
• Synthesis and characterization of new inorganic materials for photocatalytic water splitting
• Development of new materials for electrochemical carbon dioxide reduction reactions
• Investigation of the properties of transition metal oxides for energy storage and conversion applications
• Synthesis and characterization of new metal chalcogenides for optoelectronic applications
• Development of new methods for the preparation of inorganic nanoparticles with controlled size and shape
• Investigation of the reactivity and catalytic properties of metal clusters
• Synthesis and characterization of new metal-organic polyhedra (MOPs) for gas storage and separation applications
• Development of new methods for the synthesis of metal nanoparticles using environmentally friendly reducing agents
• Investigation of the properties of metal-organic frameworks for gas sensing applications
• Synthesis and characterization of new coordination polymers with potential magnetic and electronic properties
• Development of new materials for electrocatalytic water oxidation reactions
• Investigation of the properties of metal-organic frameworks for carbon capture and storage applications
• Synthesis and characterization of new metal-containing polymers with potential applications in electronics and energy storage
• Development of new methods for the synthesis of metal-organic frameworks using green solvents and renewable resources.

Physical Chemistry Research Topics

Physical Chemistry Research Topics are as follows:

• Investigation of the properties and interactions of ionic liquids in aqueous and non-aqueous solutions.
• Development of advanced analytical techniques for the study of protein structure and dynamics.
• Investigation of the thermodynamic properties of supercritical fluids for use in industrial applications.
• Development of novel nanomaterials for energy storage applications.
• Studies of the surface chemistry of catalysts for the optimization of their performance in chemical reactions.
• Development of new methods for the synthesis of complex organic molecules with improved yields and selectivity.
• Investigation of the molecular mechanisms involved in the catalysis of biochemical reactions.
• Development of new strategies for the controlled release of drugs and other bioactive molecules.
• Studies of the interaction of nanoparticles with biological systems for biomedical applications.
• Investigation of the thermodynamic properties of materials under extreme conditions of temperature and pressure.
• Development of new methods for the characterization of materials at the nanoscale.
• Investigation of the electronic and magnetic properties of materials for use in spintronics.
• Development of new materials for energy conversion and storage.
• Studies of the kinetics and thermodynamics of adsorption processes on surfaces.
• Investigation of the transport properties of ionic liquids for use in energy storage and conversion devices.
• Development of new materials for the capture and sequestration of greenhouse gases.
• Studies of the structure and properties of biomolecules for use in drug design and development.
• Investigation of the dynamics of chemical reactions in solution using time-resolved spectroscopic techniques.
• Development of new approaches for the synthesis of metallic and semiconductor nanoparticles with controlled size and shape.
• Studies of the structure and properties of materials for use in electrochemical energy storage devices.

Analytical Chemistry Research Topics

Analytical Chemistry Research Topics are as follows:

• Development and optimization of analytical techniques for the quantification of trace elements in food and environmental samples.
• Design and synthesis of novel analytical probes for the detection of biomolecules in complex matrices.
• Investigation of the fundamental mechanisms involved in the separation and detection of complex mixtures using chromatographic techniques.
• Development of sensors and biosensors for the detection of chemical and biological species in real-time.
• Investigation of the chemical and structural properties of nanomaterials and their applications in analytical chemistry.
• Development and validation of analytical methods for the quantification of contaminants and pollutants in water, air, and soil.
• Investigation of the molecular mechanisms underlying drug metabolism and toxicity using mass spectrometry.
• Development of analytical tools for the identification and quantification of drugs of abuse in biological matrices.
• Investigation of the chemical composition and properties of natural products and their applications in medicine and food science.
• Development of advanced analytical techniques for the characterization of proteins and peptides.
• Investigation of the chemistry and mechanism of action of antioxidants in foods and their impact on human health.
• Development of analytical methods for the detection and quantification of microorganisms in food and environmental samples.
• Investigation of the molecular mechanisms involved in the biosynthesis and degradation of important biomolecules such as proteins, carbohydrates, and lipids.
• Development of analytical methods for the detection and quantification of environmental toxins and their impact on human health.
• Investigation of the structure and properties of biological membranes and their role in drug delivery and disease.
• Development of analytical techniques for the characterization of complex mixtures such as petroleum and crude oil.
• Investigation of the chemistry and mechanism of action of natural and synthetic dyes.
• Development of analytical techniques for the detection and quantification of pharmaceuticals and personal care products in water and wastewater.
• Investigation of the chemical composition and properties of biopolymers and their applications in biomedicine and biomaterials.
• Development of analytical methods for the identification and quantification of essential nutrients and vitamins in food and dietary supplements.

Biochemistry Research Topics

Biochemistry Research Topics are as follows:

• The role of enzymes in metabolic pathways
• The biochemistry of DNA replication and repair
• Protein folding and misfolding diseases
• Lipid metabolism and the pathogenesis of atherosclerosis
• The role of vitamins and minerals in human metabolism
• Biochemistry of cancer and the development of targeted therapies
• The biochemistry of signal transduction pathways and their regulation
• The mechanisms of antibiotic resistance in bacteria
• The biochemistry of neurotransmitters and their roles in behavior and disease
• The role of oxidative stress in aging and age-related diseases
• The biochemistry of microbial fermentation and its applications in industry
• The biochemistry of the immune system and its response to pathogens
• The biochemistry of plant metabolism and its regulation
• The molecular basis of genetic diseases and gene therapy
• The biochemistry of membrane transport and its role in cell function
• The biochemistry of muscle contraction and its regulation
• The role of lipids in membrane structure and function
• The biochemistry of photosynthesis and its regulation
• The biochemistry of RNA splicing and alternative splicing events
• The biochemistry of epigenetics and its regulation in gene expression.

Environmental Chemistry Research Topics

Environmental Chemistry Research Topics are as follows:

• Investigating the effects of microplastics on aquatic ecosystems and their potential impact on human health.
• Examining the impact of climate change on soil quality and nutrient availability in agricultural systems.
• Developing methods to improve the removal of heavy metals from contaminated soils and waterways.
• Assessing the effectiveness of natural and synthetic antioxidants in mitigating the effects of air pollution on human health.
• Investigating the potential for using algae and other microorganisms to sequester carbon dioxide from the atmosphere.
• Studying the role of biodegradable plastics in reducing plastic waste and their impact on the environment.
• Examining the impact of pesticides and other agricultural chemicals on water quality and the health of aquatic organisms.
• Investigating the effects of ocean acidification on marine organisms and ecosystems.
• Developing new materials and technologies to reduce carbon emissions from industrial processes.
• Evaluating the effectiveness of phytoremediation in cleaning up contaminated soils and waterways.
• Studying the impact of microplastics on terrestrial ecosystems and their potential to enter the food chain.
• Developing sustainable methods for managing and recycling electronic waste.
• Investigating the role of natural processes, such as weathering and erosion, in regulating atmospheric carbon dioxide levels.
• Assessing the impact of urbanization on air quality and developing strategies to mitigate pollution in cities.
• Examining the effects of climate change on the distribution and abundance of species in different ecosystems.
• Investigating the impact of ocean currents on the distribution of pollutants and other environmental contaminants.
• Developing new materials and technologies for renewable energy generation and storage.
• Studying the effects of deforestation on soil quality, water availability, and biodiversity.
• Assessing the potential for using waste materials, such as agricultural residues and municipal solid waste, as sources of renewable energy.
• Investigating the role of natural and synthetic chemicals in regulating ecosystem functions, such as nutrient cycling and carbon sequestration.

Polymer Chemistry Research Topics

Polymer Chemistry Research Topics are as follows:

• Development of new monomers for high-performance polymers
• Synthesis and characterization of biodegradable polymers for sustainable packaging
• Design of stimuli-responsive polymers for drug delivery applications
• Investigation of the properties and applications of conductive polymers
• Development of new catalysts for controlled/living polymerization
• Synthesis of polymers with tailored mechanical properties
• Characterization of the structure-property relationship in polymer nanocomposites
• Study of the impact of polymer architecture on material properties
• Design and synthesis of new polymeric materials for energy storage
• Development of high-throughput methods for polymer synthesis and characterization
• Exploration of new strategies for polymer recycling and upcycling
• Synthesis and characterization of responsive polymer networks for smart textiles
• Design of advanced polymer coatings with self-healing properties
• Investigation of the impact of processing conditions on the morphology and properties of polymer materials
• Study of the interactions between polymers and biological systems
• Development of biocompatible polymers for tissue engineering applications
• Synthesis and characterization of block copolymers for advanced membrane applications
• Exploration of the potential of polymer-based sensors and actuators
• Design of novel polymer electrolytes for advanced batteries and fuel cells
• Study of the behavior of polymers under extreme conditions, such as high pressure or temperature.

Materials Chemistry Research Topics

Materials Chemistry Research Topics are as follows:

• Development of new advanced materials for energy storage and conversion
• Synthesis and characterization of nanomaterials for environmental remediation
• Design and fabrication of stimuli-responsive materials for drug delivery
• Investigation of electrocatalytic materials for fuel cells and electrolysis
• Fabrication of flexible and stretchable electronic materials for wearable devices
• Development of novel materials for high-performance electronic devices
• Exploration of organic-inorganic hybrid materials for optoelectronic applications
• Study of corrosion-resistant coatings for metallic materials
• Investigation of biomaterials for tissue engineering and regenerative medicine
• Synthesis and characterization of metal-organic frameworks for gas storage and separation
• Design and fabrication of new materials for water purification
• Investigation of carbon-based materials for supercapacitors and batteries
• Synthesis and characterization of self-healing materials for structural applications
• Development of new materials for catalysis and chemical reactions
• Exploration of magnetic materials for spintronic devices
• Investigation of thermoelectric materials for energy conversion
• Study of 2D materials for electronic and optoelectronic applications
• Development of sustainable and eco-friendly materials for packaging
• Fabrication of advanced materials for sensors and actuators
• Investigation of materials for high-temperature applications such as aerospace and nuclear industries.

Nuclear Chemistry Research Topics

Nuclear Chemistry Research Topics are as follows:

• Nuclear fission and fusion reactions
• Nuclear power plant safety and radiation protection
• Radioactive waste management and disposal
• Nuclear fuel cycle and waste reprocessing
• Nuclear energy and its impact on climate change
• Radiation therapy for cancer treatment
• Radiopharmaceuticals for medical imaging
• Nuclear medicine and its role in diagnostics
• Nuclear forensics and nuclear security
• Isotopic analysis in environmental monitoring and pollution control
• Nuclear magnetic resonance (NMR) spectroscopy
• Nuclear magnetic resonance imaging (MRI)
• Radiation damage in materials and radiation effects on electronic devices
• Nuclear data evaluation and validation
• Nuclear reactors design and optimization
• Nuclear fuel performance and irradiation behavior
• Nuclear energy systems integration and optimization
• Neutron and gamma-ray detection and measurement techniques
• Nuclear astrophysics and cosmology
• Nuclear weapons proliferation and disarmament.

Medicinal Chemistry Research Topics

Medicinal Chemistry Research Topics are as follows:

• Drug discovery and development
• Design and synthesis of novel drugs
• Medicinal chemistry of natural products
• Structure-activity relationships (SAR) of drugs
• Rational drug design using computational methods
• Target identification and validation
• Drug metabolism and pharmacokinetics (DMPK)
• Drug delivery systems
• Development of new antibiotics
• Design of drugs for the treatment of cancer
• Development of drugs for the treatment of neurological disorders
• Medicinal chemistry of peptides and proteins
• Development of drugs for the treatment of infectious diseases
• Discovery of new antiviral agents
• Design of drugs for the treatment of cardiovascular diseases
• Medicinal chemistry of enzyme inhibitors
• Development of drugs for the treatment of inflammatory diseases
• Design of drugs for the treatment of metabolic disorders
• Medicinal chemistry of anti-cancer agents
• Development of drugs for the treatment of rare diseases.

Food Chemistry Research Topics

Food Chemistry Research Topics are as follows:

• Investigating the effect of cooking methods on the nutritional value of food.
• Analyzing the role of antioxidants in preventing food spoilage and degradation.
• Examining the effect of food processing techniques on the nutritional value of fruits and vegetables.
• Studying the chemistry of food additives and their impact on human health.
• Evaluating the role of enzymes in food digestion and processing.
• Investigating the chemical properties and functional uses of food proteins.
• Analyzing the effect of food packaging materials on the quality and safety of food products.
• Examining the chemistry of food flavorings and the impact of flavor on consumer acceptance.
• Studying the role of carbohydrates in food texture and structure.
• Investigating the chemistry of food lipids and their impact on human health.
• Analyzing the chemical properties and functional uses of food gums and emulsifiers.
• Examining the effect of processing on the flavor and aroma of food products.
• Studying the chemistry of food preservatives and their impact on food safety.
• Investigating the chemical properties and functional uses of food fibers.
• Analyzing the effect of food processing on the bioavailability of nutrients.
• Examining the chemistry of food colorants and their impact on consumer acceptance.
• Studying the role of vitamins and minerals in food and their impact on human health.
• Investigating the chemical properties and functional uses of food hydrocolloids.
• Analyzing the effect of food processing on the allergenicity of food products.
• Examining the chemistry of food sweeteners and their impact on human health.

Industrial Chemistry Research Topics

Industrial Chemistry Research Topics are as follows:

• Development of catalysts for selective hydrogenation reactions in the petrochemical industry.
• Green chemistry approaches for the synthesis of biodegradable polymers from renewable sources.
• Optimization of solvent extraction processes for the separation of rare earth elements from ores.
• Development of novel materials for energy storage applications, such as lithium-ion batteries.
• Production of biofuels from non-food sources, such as algae or waste biomass.
• Application of computational chemistry to optimize the design of new catalysts and materials.
• Design and optimization of continuous flow processes for large-scale chemical production.
• Development of new synthetic routes for the production of pharmaceutical intermediates.
• Investigation of the environmental impact of industrial processes and development of sustainable alternatives.
• Development of innovative water treatment technologies for industrial wastewater.
• Synthesis of functionalized nanoparticles for use in drug delivery and other biomedical applications.
• Optimization of processes for the production of high-performance polymers, such as polyamides or polyesters.
• Design and optimization of process control strategies for efficient and safe chemical production.
• Development of new methods for the detection and removal of heavy metal ions from industrial effluents.
• Investigation of the behavior of surfactants in complex mixtures, such as crude oil or food products.
• Development of new materials for catalytic oxidation reactions, such as the removal of volatile organic compounds from air.
• Investigation of the properties and behavior of materials under extreme conditions, such as high pressure or high temperature.
• Development of new processes for the production of chemicals from renewable resources, such as bio-based building blocks.
• Study of the kinetics and mechanism of chemical reactions in complex systems, such as multi-phase reactors.
• Optimization of the production of fine chemicals, such as flavors and fragrances, using biocatalytic processes.

Computational Chemistry Research Topics

Computational Chemistry Research Topics are as follows:

• Development and application of machine learning algorithms for predicting chemical reactions and properties.
• Investigation of the role of solvents in chemical reactions using molecular dynamics simulations.
• Modeling and simulation of protein-ligand interactions to aid drug design.
• Study of the electronic structure and reactivity of catalysts for sustainable energy production.
• Analysis of the thermodynamics and kinetics of complex chemical reactions using quantum chemistry methods.
• Exploration of the mechanism and kinetics of enzyme-catalyzed reactions using molecular dynamics simulations.
• Investigation of the properties and behavior of nanoparticles using computational modeling.
• Development of computational tools for the prediction of chemical toxicity and environmental impact.
• Study of the electronic properties of graphene and other 2D materials for applications in electronics and energy storage.
• Investigation of the mechanisms of protein folding and aggregation using molecular dynamics simulations.
• Development and optimization of computational methods for calculating thermodynamic properties of liquids and solids.
• Study of the properties of supercritical fluids for applications in separation and extraction processes.
• Development of new methods for the calculation of electron transfer rates in complex systems.
• Investigation of the electronic and mechanical properties of carbon nanotubes for applications in nanoelectronics and nanocomposites.
• Development of new approaches for modeling the interaction of biomolecules with biological membranes.
• Study of the mechanisms of charge transfer in molecular and hybrid solar cells.
• Analysis of the structural and mechanical properties of materials under extreme conditions using molecular dynamics simulations.
• Development of new approaches for the calculation of free energy differences in complex systems.
• Investigation of the reaction mechanisms of metalloenzymes using quantum mechanics/molecular mechanics (QM/MM) methods.
• Study of the properties of ionic liquids for applications in catalysis and energy storage.

Theoretical Chemistry Research Topics

Theoretical Chemistry Research Topics are as follows:

• Quantum Chemical Studies of Excited State Processes in Organic Molecules
• Theoretical Investigation of Structure and Reactivity of Metal-Organic Frameworks
• Computational Modeling of Reaction Mechanisms and Kinetics in Enzyme Catalysis
• Theoretical Investigation of Non-Covalent Interactions in Supramolecular Chemistry
• Quantum Chemical Studies of Photochemical Processes in Organic Molecules
• Theoretical Analysis of Charge Transport in Organic and Inorganic Materials
• Computational Modeling of Protein Folding and Dynamics
• Quantum Chemical Investigations of Electron Transfer Processes in Complex Systems
• Theoretical Studies of Surface Chemistry and Catalysis
• Computational Design of Novel Materials for Energy Storage Applications
• Theoretical Analysis of Chemical Bonding and Molecular Orbital Theory
• Quantum Chemical Investigations of Magnetic Properties of Complex Systems
• Computational Modeling of Biological Membranes and Transport Processes
• Theoretical Studies of Nonlinear Optical Properties of Molecules and Materials
• Quantum Chemical Studies of Spectroscopic Properties of Molecules
• Theoretical Investigations of Reaction Mechanisms in Organometallic Chemistry
• Computational Modeling of Heterogeneous Catalysis
• Quantum Chemical Studies of Excited State Dynamics in Photosynthesis
• Theoretical Analysis of Chemical Reaction Networks
• Computational Design of Nanomaterials for Biomedical Applications

Astrochemistry Research Topics

Astrochemistry Research Topics are as follows:

• Investigating the chemical composition of protoplanetary disks and its implications for planet formation
• Examining the role of magnetic fields in the formation of complex organic molecules in space
• Studying the effects of interstellar radiation on the chemical evolution of molecular clouds
• Exploring the chemistry of comets and asteroids to better understand the early solar system
• Investigating the origin and evolution of interstellar dust and its relationship to organic molecules
• Examining the formation and destruction of interstellar molecules in shocked gas
• Studying the chemical processes that occur in the atmospheres of planets and moons in our solar system
• Exploring the possibility of life on other planets through astrobiology and astrochemistry
• Investigating the chemistry of planetary nebulae and their role in the evolution of stars
• Studying the chemical properties of exoplanets and their potential habitability
• Examining the chemical reactions that occur in the interstellar medium
• Investigating the chemical composition of supernova remnants and their impact on the evolution of galaxies
• Studying the chemical composition of interstellar grains and their role in the formation of stars and planets
• Exploring the chemistry of astrocytes and their role in the evolution of galaxies
• Investigating the formation of interstellar ice and its implications for the origin of life
• Examining the chemistry of molecular clouds and its relationship to star formation
• Studying the chemical composition of the interstellar medium in different galaxies and how it varies
• Investigating the role of cosmic rays in the formation of complex organic molecules in space
• Exploring the chemical properties of interstellar filaments and their relationship to star formation
• Studying the chemistry of protostars and the role of turbulence in the formation of stars.

Geochemistry Research Topics

Geochemistry Research Topics are as follows:

• Understanding the role of mineralogical and geochemical factors on metal mobility in contaminated soils
• Investigating the sources and fate of dissolved organic matter in aquatic systems
• Exploring the geochemical signatures of ancient sedimentary rocks to reconstruct Earth’s past atmospheric conditions
• Studying the impacts of land-use change on soil organic matter content and quality
• Investigating the impact of acid mine drainage on water quality and ecosystem health
• Examining the processes controlling the behavior and fate of emerging contaminants in the environment
• Characterizing the organic matter composition of shale gas formations to better understand hydrocarbon storage and migration
• Evaluating the potential for carbon capture and storage in geologic formations
• Investigating the geochemical processes controlling the formation and evolution of ore deposits
• Studying the geochemistry of geothermal systems to better understand energy production potential and environmental impacts
• Exploring the impacts of climate change on the biogeochemistry of terrestrial ecosystems
• Investigating the geochemical cycling of nutrients in coastal marine environments
• Characterizing the isotopic composition of minerals and fluids to understand Earth’s evolution
• Developing new analytical techniques to better understand the chemistry of natural waters
• Studying the impact of anthropogenic activities on the geochemistry of urban soils
• Investigating the role of microbial processes in geochemical cycling of elements in soils and sediments
• Examining the impact of wildfires on soil and water chemistry
• Characterizing the geochemistry of mineral dust and its impact on climate and biogeochemical cycles
• Investigating the geochemical factors controlling the release and transport of contaminants from mine tailings
• Exploring the biogeochemistry of wetlands and their role in carbon sequestration and nutrient cycling.

Electrochemistry Research Topics

Electrochemistry Research Topics are as follows:

• Development of high-performance electrocatalysts for efficient electrochemical conversion of CO2 to fuels and chemicals
• Investigation of electrode-electrolyte interfaces in lithium-ion batteries for enhanced battery performance and durability
• Design and synthesis of novel electrolytes for high-energy-density and stable lithium-sulfur batteries
• Development of advanced electrochemical sensors for the detection of trace-levels of analytes in biological and environmental samples
• Analysis of the electrochemical behavior of new materials and their electrocatalytic properties in fuel cells
• Study of the kinetics of electrochemical reactions and their effect on the efficiency and selectivity of electrochemical processes
• Development of novel strategies for the electrochemical synthesis of value-added chemicals from biomass and waste materials
• Analysis of the electrochemical properties of metal-organic frameworks (MOFs) for energy storage and conversion applications
• Investigation of the electrochemical degradation mechanisms of polymer electrolyte membranes in fuel cells
• Study of the electrochemical properties of 2D materials and their applications in energy storage and conversion devices
• Development of efficient electrochemical systems for desalination and water treatment applications
• Investigation of the electrochemical properties of metal-oxide nanoparticles for energy storage and conversion applications
• Analysis of the electrochemical behavior of redox-active organic molecules and their application in energy storage and conversion devices
• Study of the electrochemical behavior of metal-organic frameworks (MOFs) for the catalytic conversion of CO2 to value-added chemicals
• Development of novel electrode materials for electrochemical capacitors with high energy density and fast charge/discharge rates
• Investigation of the electrochemical properties of perovskite materials for energy storage and conversion applications
• Study of the electrochemical behavior of enzymes and their application in bioelectrochemical systems
• Development of advanced electrochemical techniques for the characterization of interfacial processes in electrochemical systems
• Analysis of the electrochemical behavior of nanocarbons and their application in electrochemical energy storage devices
• Investigation of the electrochemical properties of ionic liquids for energy storage and conversion applications.

Surface Chemistry Research Topics

Surface Chemistry Research Topics are as follows:

• Surface modification of nanoparticles for enhanced catalytic activity
• Investigating the effect of surface roughness on the wetting behavior of materials
• Development of new materials for solar cell applications through surface chemistry techniques
• Surface chemistry of graphene and its applications in electronic devices
• Surface functionalization of biomaterials for biomedical applications
• Characterization of surface defects and their effect on material properties
• Surface modification of carbon nanotubes for energy storage applications
• Developing surface coatings for corrosion protection of metals
• Synthesis of self-assembled monolayers on surfaces for sensor applications
• Surface chemistry of metal-organic frameworks for gas storage and separation
• Investigating the role of surface charge in protein adsorption
• Developing surfaces with superhydrophobic or superoleophobic properties for self-cleaning applications
• Surface functionalization of nanoparticles for drug delivery applications
• Surface chemistry of semiconductors and its effect on photovoltaic properties
• Development of surface-enhanced Raman scattering (SERS) substrates for trace analyte detection
• Surface functionalization of graphene oxide for water purification applications
• Investigating the role of surface tension in emulsion formation and stabilization
• Surface modification of membranes for water desalination and purification
• Synthesis and characterization of metal nanoparticles for catalytic applications
• Development of surfaces with controlled wettability for microfluidic applications.

Atmospheric Chemistry Research Topics

Atmospheric Chemistry Research Topics are as follows:

• The impact of wildfires on atmospheric chemistry
• The role of aerosols in atmospheric chemistry
• The chemistry and physics of ozone depletion in the stratosphere
• The chemistry and dynamics of the upper atmosphere
• The impact of anthropogenic emissions on atmospheric chemistry
• The role of clouds in atmospheric chemistry
• The chemistry of atmospheric particulate matter
• The impact of nitrogen oxides on atmospheric chemistry and air quality
• The effects of climate change on atmospheric chemistry
• The impact of atmospheric chemistry on climate change
• The chemistry and physics of atmospheric mercury cycling
• The impact of volcanic eruptions on atmospheric chemistry
• The chemistry and physics of acid rain formation and effects
• The role of halogen chemistry in the atmosphere
• The chemistry of atmospheric radicals and their impact on air quality and health
• The impact of urbanization on atmospheric chemistry
• The chemistry and physics of stratospheric polar vortex dynamics
• The role of natural sources (e.g. ocean, plants) in atmospheric chemistry
• The impact of atmospheric chemistry on the biosphere
• The chemistry and dynamics of the ozone hole over Antarctica.

Photochemistry Research Topics

Photochemistry Research Topics are as follows:

• Investigating the mechanisms of photoinduced electron transfer reactions in organic photovoltaic materials.
• Developing novel photoredox catalysts for photochemical reactions.
• Understanding the effects of light on DNA and RNA stability and replication.
• Studying the photochemistry of atmospheric pollutants and their impact on air quality.
• Designing new photoresponsive materials for advanced photonic and electronic devices.
• Exploring the photochemistry of metalloporphyrins for potential applications in catalysis.
• Investigating the photochemistry of transition metal complexes and their use as photodynamic therapy agents.
• Developing new photocatalytic systems for sustainable energy production.
• Studying the photochemistry of natural products and their potential pharmaceutical applications.
• Investigating the role of light in the formation and degradation of environmental contaminants.
• Designing new photochromic materials for smart windows and displays.
• Exploring the photochemistry of carbon nanomaterials for energy storage and conversion.
• Developing new light-driven molecular machines for nanotechnology applications.
• Investigating the photochemistry of organic dyes for potential applications in dye-sensitized solar cells.
• Studying the effects of light on the behavior of biological macromolecules.
• Designing new photoresponsive hydrogels for drug delivery applications.
• Exploring the photochemistry of semiconductor nanoparticles for potential applications in quantum computing.
• Investigating the mechanisms of photochemical reactions in ionic liquids.
• Developing new photonic sensors for chemical and biological detection.
• Studying the photochemistry of transition metal complexes for potential applications in water splitting and hydrogen production.

About the author

Muhammad Hassan

Researcher, Academic Writer, Web developer

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Co-Designing the Future of Computational Chemistry

New research informs the development of foundational models through co-design

Researchers developed a set of optimization techniques for graph neural networks on intelligence processing units.

(Composite image by Donald Jorgensen | Pacific Northwest National Laboratory)

In the field of computational chemistry , researchers use computers to calculate and predict the properties of chemicals and materials. Modeling these properties accurately can be expensive in terms of computational time and energy.

Machine learning techniques can help make these predictions more efficient. Researchers from Pacific Northwest National Laboratory (PNNL) , the University of Washington (UW), Graphcore, and IBM Research developed a faster way to train machine learning models through hardware–software co-design. Their research was published in the Journal of Chemical Theory and Computation .

“In chemical calculations, the geometries of atoms are represented as graphs,” said Sutanay Choudhury , who is a Chief Scientist of data sciences at PNNL. “Thus, we focused on a type of machine learning called graph neural networks—GNNs—for chemical structure and property prediction and optimized their training.”

Using Graphcore’s Intelligence Processing Unit (IPU)—a processor designed for artificial intelligence-based workloads, the researchers developed a new hardware–software co-design approach to scale up the training of GNN-based models.

They first built a set of optimization techniques for execution of the GNNs. These techniques take advantage of the high-bandwidth local memory and fast interconnect of the Graphcore system architecture to improve GNN training time. The researchers also built these techniques in a way that allows the IPU-trained atomistic GNNs to support transfer learning of custom models to graphics processing units (GPUs), and central processing units (CPUs).

“After pre-training our GNNs on IPUs, we found that we could fine-tune the GNN on a single GPU with significantly less data than we could without pre-training,” said Choudhury. “This means a pre-trained model could allow for more research at a lower computational cost—setting the stage for potential atomistic foundational models in the future.”

Developing new molecular modeling capabilities such as these are one of the goals of the Computational and Theoretical Chemistry Institute (CTCI) at PNNL, where Choudhury serves as Deputy Director. CTCI Director Sotiris Xantheas co-authored the paper with Choudhury.

“The CTCI supports the advancement of computational chemistry through close collaborations between domain scientists, data scientists, and computer scientists,” said Xantheas. “From the development of new software for electronic structure calculations to the incorporation of physics-informed machine learning techniques, we formulate new solutions for scientific problems on a variety of leadership computing facility architectures.”

PNNL researchers Jesun Firoz , Jenna (Bilbrey) Pope , Henry Sprueill, and Ang Li also contributed to the research paper. In addition to his primary appointment at PNNL, Xantheas is also an affiliate professor at the University of Washington .

This work was partially supported by the ExaLearn Co-design Center within the Exascale Computing Project , a collaborative effort between the Department of Energy’s (DOE’s) Office of Science (SC) and the National Nuclear Security Administration. It was also supported from the Center for Scalable Predictive Methods for Excitations and Correlated Phenomena (SPEC) ,  which is funded by the U.S. Department of Energy, Office of Science, Basic Energy Sciences, Chemical Sciences, Geosciences and Biosciences Division, as part of the Computational Chemical Sciences (CCS) program under FWP 70942 at Pacific Northwest National Laboratory (PNNL), a multiprogram national laboratory operated by Battelle for the U.S. Department of Energy. This research was partially supported by the DOE-SC, Advanced Scientific Computing Research program, under CENATE – the Center for Advanced Technology Evaluation . Additionally,  PNNL is advancing work in AI technology through its  Center for AI .  

Published: April 25, 2024

Research topics

Lab-level communications priority topics.

100+ Great Chemistry Research Topics

Table of contents

• 1 What are the best chemistry research topics?
• 2 5 Tips for Writing Chemistry Research Papers
• 3 Chemical Engineering Research Topics
• 4 Organic Сhemistry Research Topics
• 5 Іnorganic Сhemistry Research Topics
• 6 Biomolecular Сhemistry Research Topics
• 7 Analytical Chemistry Research Topics
• 8 Computational Chemistry Research Topics
• 9 Physical Chemistry Research Topics
• 10 Innovative Chemistry Research Topics
• 11 Environmental Chemistry Research Topics
• 12 Green Chemistry Research Topics
• 13.1 Conclusion

Do you need a topic for your chemistry research paper? Are you unsure of where to start? Don’t worry – we’re here to help. In this post, we’ll go over a series of the best chemistry research paper topics as well as Tips for Writing Chemistry Research Papers on different topics. By the time you finish reading this post, you’ll have plenty of ideas to get started on your next research project!

There are many different subfields of chemistry, so it can be tough to find interesting chemistry topics to write about. If you’re struggling to narrow down your topic, we’ll go over lists of topics in multiple fields of study.

What are the best chemistry research topics?

Doing research is important to help scientists learn more about the world around us. By researching different compounds and elements, we can learn more about how they interact with one another and how they can be used to create new products or improve existing ones.

There are many different topics that you can choose to research in chemistry. Here are just a few examples:

• The history of chemistry and how it has evolved over time
• How different chemicals react with one another
• How to create new compounds or improve existing ones
• The role of chemistry in the environment
• The health effects of different chemicals

5 Tips for Writing Chemistry Research Papers

Once you have chosen a topic for your research paper , it is important to follow some tips to ensure that your paper is well-written and accurate. Here are a few tips to get you started:

• Start by doing some background research on your topic. This will help you understand the basics of the topic and give you a good foundation to build your paper on.
• Make sure to cite all of the sources that you use in your paper. This will help to show where you got your information and will also help to add credibility to your work.
• Be sure to proofread your paper before you submit it. This will ensure that there are no errors and that your paper is clear and concise.
• Get help from a tutor or friend if you are struggling with your paper. They may be able to offer helpful advice or feedback.
• Take your time when writing your research paper . This is not a race, and it is important to make sure that you do a good job on your research.

By following these tips, you can be sure that your chemistry research paper will be a success! So what are you waiting for? Let’s go over some of the best research paper topics out there.

Chemical Engineering Research Topics

Chemical Engineering is a branch of engineering that deals with the design and application of chemical processes. If you’re wondering how to choose a paper topic, here are some ideas to inspire you:

• How to create new alloy compounds or improve existing ones
• The health effects of the food industry chemicals
• Chemical engineering and sustainable development
• The future of chemical engineering
• Chemical engineering and the food industry
• Chemical engineering and the pharmaceutical industry
• Chemical engineering and the cosmetics industry
• Chemical engineering and the petrochemical industry

These are just a few examples – there are many more possibilities out there! So get started on your research today. Who knows what you might discover!

Organic Сhemistry Research Topics

Organic chemistry is the study of carbon-containing molecules. There are many different organic chemistry research topics that a student could choose to focus on and here are just a few examples of possible research projects in organic chemistry:

• Investigating new methods for synthesizing chiral molecules
• Studying the structure and reactivity of carbon nanotubes
• Investigating metal complexes with organometallic ligands
• Designing benzene derivatives with improved thermal stability
• Exploring new ways to control the stereochemistry of chemical reactions
• Studying the role of enzymes in organic synthesis
• Investigating new strategies for combating drug resistance
• Developing new methods for detecting explosives residues
• Studying the photochemistry of organic molecules
• Studying the behavior of organometallic compounds in biological systems

Іnorganic Сhemistry Research Topics

Inorganic Chemistry is the study of the chemistry of materials that do not contain carbon. Unlike other chemistry research topics, these include elements such as metals, minerals, and inorganic compounds. If you are looking for inorganic chemistry research topics on inorganic chemistry, here are some ideas to get you started:

• How different metals react with one another
• How to create new alloys or improve existing ones
• The role of inorganic chemistry in the environment
• Inorganic chemistry and sustainable development
• The future of inorganic chemistry
• Inorganic chemistry and the food industry
• Inorganic chemistry and the pharmaceutical industry
• Atomic structure progressive scale grading
• Inorganiс Сhemistry and the cosmetics industry

Biomolecular Сhemistry Research Topics

Biomolecular chemistry is the study of molecules that are important for life. These molecules can be found in all living things, from tiny bacteria to the largest animals. Researchers who work in this field use a variety of techniques to learn more about how these molecules function and how they interact with each other.

If you are looking for essential biomolecular chemistry research topics, here are some ideas to get you started:

• The structure and function of DNA
• The structure and function of proteins
• The role of carbohydrates in the body
• The role of lipids in the body
• How enzymes work
• The role of biochemistry in heart disease
• Cyanides and their effect on the body
• The role of biochemistry in cancer treatment
• The role of biochemistry in Parkison’s disease treatment
• The role of biochemistry in the immune system

The possibilities are endless for someone willing to dedicate some time to research.

Analytical Chemistry Research Topics

Analytical Chemistry is a type of chemistry that helps scientists figure out what something is made of. This can be done through a variety of methods, such as spectroscopy or chromatography. If you are looking for research topics, here are some ideas to get you started:

• How food chemicals react with one another
• Mass spectrometry
• Analytical aspects of gas and liquid chromatography
• Analytical chemistry and sustainable development
• Atomic absorption spectroscopy methods and best practices
• Analytical chemistry and the pharmaceutical industry in Ibuprofen consumption
• Analytical chemistry and the cosmetics industry in UV protectors
• Dispersive x-ray analysis of damaged tissues

Analytical chemistry is considered by many a complex science and there is a lot yet to be discovered in the field.

Computational Chemistry Research Topics

Computational chemistry is a way to use computers to help chemists understand chemical reactions. This can be done by simulating reactions or by designing new molecules. If you are looking for essential chemistry research topics in computational chemistry, here are some ideas to get you started:

• Molecular mechanics simulation
• Reaction rates of complex chemical reactions
• Designing new molecules: how can simulation help
• The role of computers in the study of quantum mechanics
• How to use computers to predict chemical reactions
• Using computers to understand organic chemistry
• The future of computational chemistry in organic reactions
• The impacts of simulation on the development of new medications
• Combustion reaction simulation impact on engine development
• Quantum-chemistry simulation review

Computers are cutting-edge technology in chemical research and this relatively new field of study has a ton yet to be explored.

Physical Chemistry Research Topics

Physical chemistry is the study of how matter behaves. It looks at the physical and chemical properties of atoms and molecules and how they interact with each other. If you are looking for physical chemistry research topics, here are some ideas to get you started:

• Standardization of pH scales
• Structure of atom on a quantum scale
• Bonding across atoms and molecules
• The effect of temperature on chemical reactions
• The role of light in in-body chemical reactions
• Chemical kinetics
• Surface tension and its effects on mixtures
• The role of pressure in chemical reactions
• Rates of diffusion in gases and liquids
• The role of entropy in chemical reactions

Here are just a few samples, but there are plenty more options! Start your research right now!

Innovative Chemistry Research Topics

Innovative chemistry is all about coming up with new ideas and ways to do things. This can be anything from creating new materials to finding new ways to make existing products. If you are looking for ground-breaking chemistry research topics, here are some ideas to get you started:

• Amino acids side chain effects in protein folding
• Chemistry in the production of nanomaterials
• The role of enzymes in chemical reactions
• Photocatalysis in 3D printing
• Avoiding pesticides in agriculture
• Combining chemical and biological processes
• Gene modification in medicinal chemistry
• The role of quantum mechanics in chemical reactions
• Astrochemical research on extraterrestrial molecules
• Spectroscopy signatures of pressurized organic components

If you need a hand, there are several sites that also offer research papers for sale and can be a great asset as you work to create your own research papers.

Whatever route you decide to take, good luck! And remember – the sky’s the limit when it comes to research! So get started today and see where your studies may take you. Who knows, you might just make a breakthrough discovery!

Environmental Chemistry Research Topics

Environmental Chemistry is the study of how chemicals interact with the environment. This can include anything from the air we breathe to the water we drink. If you are looking for environmental chemistry research topics, here are some ideas to get you started:

• Plastic effects on ocean life
• Urban ecology
• The role of carbon in climate change
• Air pollution and its effects
• Water pollution and its effects
• Chemicals in food and their effect on the body
• The effect of chemicals on plant life
• Earth temperature prediction models

A lot of research on the environment is being conducted at the moment because the environment is in danger. There are a lot of environmental problems that need to be solved, and research is the key to solving them.

Green Chemistry Research Topics

Green chemistry is the study of how to make products and processes that are environmentally friendly. This can include anything from finding new ways to recycle materials to developing new products that are biodegradable. If you are looking for green chemistry research topics, here are some ideas to get you started:

• Recycling and reuse of materials
• Developing biodegradable materials
• Improving existing recycling processes
• Green chemistry and sustainable development
• The future of green chemistry
• Green chemistry and the food industry
• Green chemistry and the pharmaceutical industry
• Green chemistry and the cosmetics industry

A more environmentally friendly world is something we all aspire for and a lot of research has been conducted on how we can achieve this, making this one of the most promising areas of study. The results have been varied, but there are a few key things we can do to make a difference.

Controversial Chemistry Research Topics

Controversial chemistry is all about hot-button topics that people are passionate about. This can include anything from the use of chemicals in warfare to the health effects of different chemicals. If you are looking for controversial topics to write about , here are some ideas to get you started:

• The use of chemicals in warfare
• Gene modification in human babies
• Bioengineering
• How fast food chemicals affect the human brain
• The role of the government in regulating chemicals
• Evolution of cigarette chemicals over time
• Chemical effects of CBD oils
• Antidepressant chemical reactions
• Synthetic molecules replication methods
• Gene analysis

Controversial research papers often appear in the media before it has been peer-reviewed and published in a scientific journal. The reason for this is that the media is interested in stories that are new, exciting, and generate a lot of debate.

Chemistry is an incredibly diverse and interesting field, with many controversial topics to write about. If you are looking for a research topic, consider the examples listed in this article. With a little bit of effort, you are sure to find a topic that is both interesting and within your skillset.

In order to be a good researcher, it is important to be able to think critically and solve problems. However, innovation in chemistry research can be challenging. When thinking about how to innovate, it is important to consider both the practical and theoretical aspects of your research. Additionally, try to build on the work of others in order to create something new and unique. With a little bit of effort, you are sure to be able to find a topic that is both interesting and within your skillset.

Happy writing!

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Event Title OTP Town Hall: CMC Readiness for Gene Therapy BLAs June 4, 2024

The FDA’s Center for Biologics Evaluation and Research (CBER) Office of Therapeutic Products (OTP) is hosting its next virtual town hall on Tuesday, June 4, 2024, to answer stakeholder questions regarding the chemistry, manufacturing, and controls (CMC) information submitted with biologics license applications (BLAs) for gene therapy products. Experts from OTP’s Office of Gene Therapy CMC will be on hand to answer questions.

Focus for This Town Hall: Gene Therapy BLA CMC Readiness

The FDA requires sponsors to provide CMC information as part of investigational new drug, biologics license, and new drug applications. For gene therapies and other biologic products, the CMC information should describe the sponsor’s commitment to perform manufacturing and testing to assure product safety, identity, quality, purity, and strength (including potency). The focus of this virtual town hall is to answer questions related to CMC data and information needed to support pre-BLA meetings or original BLA submissions, including the commercial manufacturing process, product comparability (if applicable), stability data, and more. For more information, please view materials from previous town halls on gene therapy CMC . 

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Please note, the FDA is not able to comment on or answer questions regarding specific investigational products, biologics applications, or draft guidance documents during the town hall. Further, questions considered inappropriate or out of scope for the event will not be addressed.

About the OTP Town Hall Series

OTP launched its virtual town hall series to engage with product development stakeholders and discuss topics related to OTP-regulated products. The town halls have a question-and-answer format with the goal of providing regulatory information to stakeholders to advance drug development. Learn more about OTP  and view recordings from our previous town hall events .

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